New Medical Treatment for Androgenetic Alopecia

نویسندگان

  • S. Y. Cheng
  • Kenneth J. Washenik
چکیده

Dihydrotestosterone(DHT) has played the pathogenic role in androgenetic alopecia. Patients with genetic deficiency of 5 alpha-reductase type II enzyme, which converts testosterone to DHT, do not have androgenic alopecia. The conversion of testosterone to DHT at hair follicles leads to miniaturization. In scalp biopsy, the tissue DHT level is significantly increased in balded area than non-balded area.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Re-activation of Wnt/β-catenin Signaling Pathway in Hair Follicle Stem Cells in Treatment of Androgenetic Alopecia

Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem cells are alive, but quiescence in androgenetic alopecia and are potentially active and can proliferate and differentiate, then regenerate hai...

متن کامل

Male androgenetic alopecia.

IMPORTANCE OF THE FIELD Androgenetic alopecia affects up to 80% of males by the age of 80. The synonym 'male-pattern hair loss' highlights the fact that hair loss occurs in a defined and reproducible pattern. Hair loss results in reduced self esteem, loss of confidence and anxiety in affected men. An effective treatment for hair baldness would be desirable. AREAS COVERED IN THIS REVIEW In and...

متن کامل

Association of androgenetic alopecia and hypertension.

Androgenetic alopecia is considered to be associated with coronary heart disease but the explanation of this association remains unknown. Hypertension is highly prevalent in patients with coronary heart disease. Essential hypertension is linked to hyperaldosteronism and spironolactone, an antihypertensive drug which is a mineralocorticoid receptor antagonist, has been used for a long time in th...

متن کامل

The meaning of baldness and implications for treatment.

From the Lkpartment of Anthropology, University of MichiganDearborn, College of Arts, Sciences, and L.&D-S, Dearborn, Michigan Use of therapies to improve an individual’s appearance is not a new medical concept. Androgenetic alopecia has been recognized as a disorder since the time of Hippocrates,’ and since that time, a variety of preparations and surgical procedures have been used as treatmen...

متن کامل

Minoxidil in combination with Tretinoin vs. Minoxidil in the treatment of male androgenic alopecia: A randomized, double-blind, parallel clinical trial

Background: Minoxidil is currently an approved treatment for androgenetic alopecia. Topical tretinoin can enhance skin absorption of minoxidil. Objective: This study has been done in order to determine the efficacy and safety of the solution of 0.5% minoxidil+0.05% tretinoin compared to 2% minoxidil in androgenetic alopecia in men. Patients and Methods: In a randomized, double-blind, parallel-g...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 1999